3-氰基吡啶

The Henry's Law constant for 3-pyridinecarbonitrile is 2.74X10-7 atm-cu m/mole(1). This Henry's Law constant indicates that 3-pyridinecarbonitrile is not expected to volatilize from water and moist soil surfaces(2). 3-Pyridinecarbonitrile is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.296 mm Hg(3).

大气命运：根据半挥发性有机化合物在大气中的气/粒子分配模型 (1)，3-吡啶腈，其在 25 °C(2) 时的蒸气压为 0.296 mm Hg，预计仅以蒸气形式存在于环境大气中 (SRC)。气相态的 3-吡啶腈在大气中被光化学产生的羟基自由基降解 (SRC)；该反应在空气中的半衰期估计为 246 天 (SRC)，根据其速率常数计算得出，该速率常数为 6.53X10^-14 cu cm/molecule-sec at 25 °C(SRC)，使用结构估算方法确定 (3)。

An estimated BCF of 3 was calculated for 3-pyridinecarbonitrile(SRC), using a log Kow of 0.36(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

ANAEROBIC: The maximum pseudo-first-order rate constant and half-life for 3-pyridinecarbonitrile in an anoxic sediment slurry from the estuary of the Tansui River (Guandu, Taipei) were 9.41 per day and 1.7 hrs, respectively(1). 3-Pyridinecarbonitrile was not transformed in the sterile control sediment slurry(1) which suggests that 3-pyridinecarbonitrile may degrade in the environment at least under anaerobic conditions(SRC).

The rate constant for the vapor-phase reaction of 3-pyridinecarbonitrile with photochemically-produced hydroxyl radicals has been estimated as 6.53X10-14 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 246 days at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(1). 3-Pyridinecarbonitrile is expected to undergo slow hydrolysis in the environment based upon the slow hydrolysis of other aromatic nitriles, eg, benzonitrile(2). 3-Pyridinecarbonitrile is also not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum (>290 nm)(SRC).

The Koc of 3-pyridinecarbonitrile is estimated as 37(SRC), using a measured log Kow of 0.36(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 3-pyridinecarbonitrile is expected to have very high mobility in soil(SRC).

3-Pyridinecarbonitrile's production and use in organic synthesis(1) may result in its release to the environment through various waste streams(SRC).

USDA APHIS Chemical Effects: collection=usda_chemeffect&query_type=synonym&query='^100-54-9$'

Occupational exposure to 3-pyridinecarbonitrile may occur through inhalation and dermal contact with this compound at workplaces where 3-pyridinecarbonitrile is produced or used. (SRC)

3-吡啶腈的合成和使用于有机合成中可能导致其通过各种废物流释放到环境中。如果释放到空气中，0.296 mm Hg 的蒸气压（在 25 °C）表明 3-吡啶腈仅以蒸气形式存在于环境大气中。气相态的 3-吡啶腈将通过与光化学产生的羟基自由基反应而在大气中被降解；该反应在空气中的半衰期估计为 246 天。如果释放到土壤中，基于估算的 Koc 值为 37，预计 3-吡啶腈具有非常高的迁移性。挥发从湿润土壤表面来说不是重要的命运过程，基于亨利定律常数为 2.74X10^-7 atm-cu m/mole。如果释放到水中，3-吡啶羧...

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