化合物详情

/AQUATIC SPECIES/ Among populations of Paracentrotus lividus living near the sewage outlet of Marseilles' conurbation, ...individuals with brown to black gonads /have been observed/. An ultrastructural study demonstrated the presence of extracellular and intracellular crystals. In the latter they are in nucleus, vacuoles and cytoplasm of phagocytic coelomocytes. An X-ray microanalysis indicates the presence of iron, chlorine and sulfur in these crystals. ...A relationship between this bioaccumulation and the release into coastal water of iron chloride from the sewage treatment plant of Marseilles /is proposed/. This element may be found in both the coelomic fluid and food of sea-urchin. It is collected and transformed by phagocytic coelomocytes. When this bioaccumulation becomes excessi...

The substance is harmful to aquatic organisms.

Occurs in nature as the mineral molysite.

NIOSH (NOES Survey 1981-1983) has statistically estimated that 108,492 workers (52,117 of these are female) are potentially exposed to ferric chloride in the US(1).

Ingestion Exposure: Abdominal pain. Vomiting. Diarrhoea. Shock or collapse.

Benzo(a)pyrene (0.5 mg), in itself weakly carcinogenic, when given in combination with ferric chloride (0.16 mg) or iodine (0.2 mg), alone noncarcinogen, induced a number of tumors of different parts of the respiratory tract of Syrian golden hamsters.

Dermatotoxin - Skin burns.

The substance can be absorbed into the body by ingestion.

/OTHER TOXICITY INFORMATION/ Diagnosis of iron intraocular foreign body has usually been based on x-ray demonstration of an opaque foreign body by establishing that the foreign body can be made to move with a magnet, but in some instances either one or both of these diagnostic measures are inconclusive, yet clinical findings suggestive of siderosis indicate that there may be an intraocular iron foreign body. To help establish the diagnosis, analysis of the aqueous humor for iron, to detect an abnormally high content, has proven useful in a few cases. Also as a help in diagnosis, particularly in eyes where surgery for cataract is required, histologic staining of an excised piece of iris or analysis of the lens for iron has been helpful diagnostically. However, to make a definite diagnosi...

LD50 Rat oral 28 mg/kg

...There is concern that the individual with metabolic defects that impair the ability to regulate iron absorption will be at risk from excessive exposure to iron, primarily as a result of acceleration of accumulation of iron in the body and an earlier onset of clinical symptoms of the disease. /Iron salts/