化合物详情

USDA APHIS Chemical Effects: collection=usda_chemeffect&query_type=synonym&query='^126-22-7$'

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), butonate, which has an estimated vapor pressure of 1.1X10-4 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase butonate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4.3 days(SRC), calculated from its rate constant of 7.5X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase butonate may be removed from the air by wet or dry deposition(SRC). Butonate is susceptible to direct photolysis by sunli...

Using a structure estimation method based on molecular connectivity indices(1), the Koc of butonate can be estimated to be 1,100(SRC). According to a classification scheme(2), this estimated Koc value suggests that butonate is expected to have low mobility in soil.

An estimated BCF of 4.1 was calculated for butonate(SRC), using an estimated log Kow of 1.7(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Henry's Law constant for butonate is estimated as 3.0X10-10 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that butonate is expected to be essentially nonvolatile from water surfaces(2). Butonate's Henry's Law constant indicates that volatilization from moist soil surfaces is not expected to occur(SRC). Butonate is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.1X10-4 mm Hg(SRC), determined from a fragment constant method(3).

The rate constant for the vapor-phase reaction of butonate with photochemically-produced hydroxyl radicals has been estimated as 7.5X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 4.3 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). A base-catalyzed second-order hydrolysis rate constant of 4.7X10-2 L/mole-sec(SRC) was estimated using a structure estimation method(2); this corresponds to half-lives of 4.7 years, 170 days, and 17 days at pH values of 7, 8, and 9, respectively(2). In a aqueous environment hydrolysis study, butonate was found to hydrolyze to the hydroxy deriviative chlorophos in acid media (pH 1.9 to 5) and dehydrochlorination occurred in alkaline media (pH 7....

Spraying 45 mg butonate/cow after morning milking gave residues of 0.03-0.1 mg/kg in milk from evening milking and equal residues of butonate metabolite, trichlorfon.

Butonate's former production and use as an insecticide(1) may have resulted in its direct release to the environment(SRC).

... Toxic by inhalation, skin absorption, and/or ingestion. /Organophosphorus pesticide/

Butonate's former production and use as an insecticide may have resulted in its direct release to the environment. If released to air, an estimated vapor pressure of 1.1X10-4 mm Hg at 25 °C indicates butonate will exist in both the vapor and particulate phases in the atmosphere. Vapor-phase butonate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 4.3 days. Particulate-phase butonate will be removed from the atmosphere by wet or dry deposition. Butonate is susceptible to direct photolysis by sunlight and the photolysis products of an aqueous solution of butonate exposed to UV light were found to be vinyl butonate, chlorophos, DDVP, and HCl. If released to soil, butonate is expected t...

Other Poison - Organophosphate

/OTHER TOXICITY INFORMATION/ Its relatively low mammalian toxicity is attributed to rapid hydrolysis of the butyl and phosphate ester groupings.

/GENOTOXICITY/ Mechanism of genotoxic activity of butonate was investigated using the Ames test. Butonate was not mutagenic.