化合物详情

The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in aquatic organisms. The substance may cause long-term effects in the aquatic environment. It is strongly advised not to let the chemical enter into the environment.

Mercurous sulfate becomes gray on exposure to light with prodn of mercury and mercuric sulfate.

Common symptoms include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), edema (swelling), and desquamation (dead skin peels off in layers). (A5)

Mercury poisoning is treated by immediate decontamination and chelation therapy using DMSA, DMPS, DPCN, or dimercaprol. (A7)

LD50: 57 mg/kg (Oral, Rat) (T14) LD50: 6300 ug/kg (Intraperitoneal, Mouse) (T72)

Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7)

ACGIH Carcinogen - Not Classifiable.

Oral (L7); inhalation (L7); dermal (L7)

High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein...

Chronic Inhalation: 0.0002 mg/m3 (L134)

Systemic toxicity may begin within a few hours after exposure to mercury and last for days. A strong metallic taste is followed by stomatis with gingival irritation, foul breath, and loosening of the teeth. The most serious ... effect is renal toxicity. ...

3, not classifiable as to its carcinogenicity to humans. (L135)

LD50 oral rat 57 mg/kg

MERCURIC SULFATE DIETARY LEVELS IN SINGLE COMB WHITE LEGHORN CHICKENS & JAPANESE QUAILS UP TO 200 PPM OF HG, HAD ONLY SMALL EFFECTS, IF ANY, UPON EGG PRODN, FERTILITY, HATCHABILITY, EGG SHELL STRENGTH, MORBIDITY, & MORTALITY.

Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient with severe pulmonary edema or respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Mercury and related compounds/