化合物详情

... EXPOSURE TO TITANIUM IS MAINLY ASSOC WITH METAL, DIOXIDE, CARBIDE, OR TETRACHLORIDE. EXPOSURE ... USUALLY IN FORM OF DUST BUT EXPOSURES TO FUMES & VAPORS OCCUR DURING HANDLING OF TITANIUM TETRACHLORIDE.

... REPORT OF LUNG CHANGES IN ANIMALS EXPOSED FOR 5 MO TO TITANIUM COMBINED WITH CARBON. CHANGES WERE SAID TO RESEMBLE SILICOSIS, LESIONS NOT FOUND IN ANIMALS EXPOSED FOR SEVERAL YR TO DUST OF ... CARBOLOY WHICH CONTAINS TITANIUM CARBON CMPD ... .

Food is considered to be the principal source of titanium exposure for humans. The chemical and biological kinetics and metabolism of titanium are discussed. The only carcinogenic effects of titanium thus far reported have been the development of fibrosarcomas at the injection sites in exposed rats. There is no evidence that titanium is carcinogenic in humans. /It was concluded/ that the current extent of exposure to titanium of the general population does not pose a health risk.

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/