一键配货
化合物详情
CAS7782-65-2
分子式GeH4
分子量76.67 g/mol
危化品
Physical Description | Germane is a colorless gas with a pungent odor. It is flammable. The gas is heavier than air and a flame can flash back to the source of leak very easily. It is toxic by inhalation. Prolonged exposure of the containers to fire or intense heat may result in their violent rupturing and rocketing. It is used in making electronics.
科学粮草官-词典编辑部，修订于：2026-07-06
Toxicity
ToxicitySymptoms
malaise (vague feeling of discomfort), headache, dizziness, fainting; dyspnea (breathing difficulty); nausea, vomiting; kidney injury; hemolytic effects
Target Organs
central nervous system, kidneys, blood
Toxicity Data
LC50 (mouse) = 1,380 mg/m3
Adverse Effects
Hemolytic anemia - Decreased hemoglobin or number of red blood cells.
Exposure Routes
inhalation
Non-Human Toxicity Values
LD50 Mouse oral 1250 mg/kg
Non-Human Toxicity Excerpts
/OTHER TOXICITY INFORMATION/ General toxicity of germanium is low, except for the tetrahydride germane, and few observations on toxicity of germanium in /humans/ exist. ... Germanium compounds have no mutagenic activity and may, under certain conditions, inhibit the mutagenic activity of other substances. High doses of germanium may result in an increased embryonic resorption, but possible malformations have been reported only after administration of dimethyl germanium oxide to pregnant animals.
Antidote and Emergency Treatment
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Administer furosemide (Lasix) ... .Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of 0.9% saline (NS) or lactated Ringer's (LR). Titrate flow to maintain urine output. Treat hypotension with cautious fluid administration. Vasopressors should be used only if fluid administration can not maintain an adequate blood pressure. Watch for signs of fluid overload ... . Administer sodium bicarbonate IV push, BY DIRECT PHYSICIAN ORDER. T...
