化合物详情

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,1,2,2-tetrachloro-1-fluoroethane, which has an estimated vapor pressure of 19 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,1,2,2-tetrachloro-1-fluoroethane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1300 days(SRC), calculated from its rate constant of 1.2X10-14 cu cm/molecule-sec at 25 °C(SRC) determined using a structure estimation method(3). Stratospheric photolysis of 1,1,2,2-tetrachloro-1-fluoroethane frees chlorine radicals which can participate in...

Using a structure estimation method based on molecular connectivity indices(1), the Koc for 1,1,2,2-tetrachloro-1-fluoroethane can be estimated to be 150(SRC). According to a classification scheme(2), this estimated Koc value suggests that 1,1,2,2-tetrachloro-1-fluoroethane is expected to have moderate mobility in soil.

An estimated BCF of 29 was calculated for 1,1,2,2-tetrachloro-1-fluoroethane(SRC), using an estimated log Kow of 2.8(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Henry's Law constant for 1,1,2,2-tetrachloro-1-fluoroethane is estimated as 0.003 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that 1,1,2,2-tetrachloro-1-fluoroethane is expected to volatilize from water surfaces(2). Based on this estimated Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 4 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 5.5 days(SRC). 1,1,2,2-Tetrachloro-1-fluoroethane's estimated Henry's Law constant(1) indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of 1,1,2,2-tetrachloro...

The rate constant for the vapor-phase reaction of 1,1,2,2-tetrachloro-1-fluoroethane with photochemically-produced hydroxyl radicals has been estimated as 1.2X10-14 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1300 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). 1,1,2,2-Tetrachloro-1-fluoroethane is unreactive in neutral and alkaline solution(2) and is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum (>290 nm). However, stratospheric photolysis of ozone depleting chemicals such as 1,1,2,2-tetrachloro-1-fluoroethane frees chlorine radicals which can participate in ozone-destroying reactions(3). The ozone-depletion potential for...

No production or use information was located for 1,1,2,2-tetrachloro-1-fluoroethane(SRC). However, the HCFCs are one class of chemicals being used to replace the CFCs which are commonly used as refrigerants, solvents, and foam blowing agents(1).

Occupational exposure to 1,1,2,2-tetrachloro-1-fluoroethane may occur through inhalation and dermal contact with this compound at workplaces where 1,1,2,2-tetrachloro-1-fluoroethane is produced or used. (SRC)

No production or use information was located for 1,1,2,2-tetrachloro-1-fluoroethane. If released to air, an estimated vapor pressure of 19 mm Hg at 25 °C indicates 1,1,2,2-tetrachloro-1-fluoroethane will exist in both the vapor and particulate phases. Vapor-phase 1,1,2,2-tetrachloro-1-fluoroethane will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1300 days. Stratospheric photolysis involving 1,1,2,2-tetrachloro-1-fluoroethane frees chlorine radicals which can participate in ozone-destroying reactions. If released to soil, 1,1,2,2-tetrachloro-1-fluoroethane is expected to have moderate mobility based upon an estimated Koc of 150. Volatilization from moist soil surfaces is expected to b...

Neurotoxin - Acute solvent syndrome