化合物详情

Obtained from ores tantalite or columbite... mixed oxides of iron, manganese, niobium and tantalum. ...Considered as rare element earth's crust contains about 0.003% of niobium and tantalum together... .

HOW RELEVANT THE TOXICITY EVIDENCE OBTAINED FROM SOLID METAL SURFACES IS TO THAT OF FINELY DIVIDED TA METAL POWDER IS CERTAINLY QUESTIONABLE. CERTAINLY ONE WOULD EXPECT TANTALUM METAL FUME TO HAVE A DIFFERENT ORDER OF TOXICITY THAN THE MORE COARSELY DIVIDED DUSTS.

irritation eyes, skin; In Animals: pulmonary irritation

Eyes, skin, respiratory system

inhalation, skin and/or eye contact

/LABORATORY ANIMALS: Subchronic or Prechronic Exposure/ In a 10 week experimental investigation the tissue reactions to implantation of standardized test pieces /of several test materials, including/ ... tantalum, ... were studied in the white rat ... After 10 weeks, no cellular infiltration was demonstrable around any of the implant materials...all appeared inert and were surrounded by a tough connective tissue.

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/