化合物详情

CAS959-24-0

分子式C12H20N2O3S.HCl

分子量308.82 g/mol g/mol

危化品

Sotalol hydrochloride is a hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. It has a role as a beta-adrenergic antagonist and an anti-arrhythmia drug. It contains a sotalol(1+).

科学粮草官-词典编辑部，修订于：2026-07-06

Toxicity

Lethal Dose

collection=toxvaldb&kind=^LD$

Drug Induced Liver Injury

References: DOI:10.1016/j.drudis.2016.02.015

Effects During Pregnancy and Lactation

Relevant published information on the effects of beta-blockade or sotalol during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.