一键配货
化合物详情
CAS997-55-7
分子式C6H9NO5
分子量175.14 g/mol g/mol
危化品
N-acetyl-L-aspartic acid is an N-acyl-L-aspartic acid in which the acyl group is specified as acetyl. It has a role as an antioxidant, a nutraceutical, a mouse metabolite, a human metabolite and a rat metabolite. It is a N-acetyl-L-amino acid and a N-acyl-L-aspartic acid. It is a conjugate acid of a N-acetyl-L-aspartate(2-).
科学粮草官-词典编辑部，修订于：2026-07-06
Toxicity
ToxicityHealth Effects
Chronically high levels of N-acetyl-aspartate are associated with Canavan Disease.
Toxicity Summary
The primary proposed functions of N-acetylaspartic acid include: 1) A neuronal osmolyte that is involved in fluid balance in the brain; 2) a source of acetate for lipid and myelin synthesis in oligodendrocytes, the glial cells that myelinate neuronal axons; 3) a precursor for the synthesis of the important neuronal dipeptide N-acetylaspartylglutamate; 4) N-acetylaspartic acid may also be involved in energy production from the amino acid glutamate in neuronal mitochondria. Excess amounts of N-acetyl-L-aspartic acid accumulated in plasma, spinal fluid, and urine have been found to be toxic. On the other hand, decreased concentration of N-acetyl-L-aspartic acid according to the in vivo spectrum of the brain has been related to disorders such as hypoacetylaspartia.
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
