化合物详情

/SPECIAL STUDIES/ In September 1987, the Goiania radiological accident involving a source of 137Cs culminated in about 140 victims who presented internal and/or external contamination and/or external exposure to radiation and/or radiation burns. Internal contamination was verified through analysis of urine and fecal samples. Internal contamination was also evaluated by measurements performed at the whole-body counter installed in Goiania in November 1987. To enhance the decorporation of 137Cs, patients were treated with the following: 1 ) Prussian Blue, oral administration, in 46 patients; 2 ) diuretics, oral administration, in 17 patients; 3 ) induced perspiration, increasing 137Cs elimination. These procedures were done under rigorous clinical evaluation and considering the data from...

LD50 Rat ip 1.5 g/kg

The FDA has determined that the 500 mg Prussian blue capsules, when manufactured under the conditions of an approved New Drug Application (NDA), can be found safe and effective for the treatment of known or suspected internal contamination with radioactive cesium, radioactive thallium, or non-radioactive thallium. Prussian blue can be used to treat contamination that may occur as a result of a routine accidental poisoning, as well as contamination associated with a terrorist event. Prussian blue works by trapping thallium and cesium in the intestine, so that they can be passed out of the body in the stool rather than be re-absorbed. If persons are exposed to radioactive cesium, radioactive thallium, or non-radioactive thallium, taking Prussian blue may reduce the risk of death and major...