化合物详情

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

IDENTIFICATION AND USE: Antimony trifluoride exists in three known crystallin modifications. It is used to catalyze fluorinations by hydrogen fluoride, manufacture of chlorofluorides, in dyeing, usually in form of double salts, manufacture of pottery and porcelains. HUMAN STUDIES: Symptoms of exposure include severe gastritis or gastroenteritis with abdominal pain, retching, and prolonged vomiting, beginning 10-60 min after ingestion. Vomitus may become bloody. Diarrhea is observed, and the feces are watery and later tarry. Dehydration becomes intense. The exposure could further progress to shock, pallor, cyanosis, and coldness, rapid, weak or imperceptible pulse, low blood pressure, rapid and shallow respirations. Sometimes breathing is deep and rapid, reflecting an accompanying metabo...

/OTHER TOXICITY INFORMATION/ Chronic inhalation of subtoxic doses of antimony salts causes interstitial pneumonitis, intraalveolar lipoid deposits, and liver and cardiac damage. /Antimony salts/

A4; Not classifiable as a human carcinogen. /Fluorides, as F/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacain...