化合物详情

CAS7787-32-8

分子式BaF2

分子量175.32 g/mol

危化品

Barium fluoride is a fluoride of barium that occurs naturally as the mineral frankdicksonite. It is used to make optical components such as lenses, in to production of welding agents, and in aluminum refining. Barium fluoride can also be used as a scintillator for the detection of X-rays and gamma rays. Barium is a metallic alkaline earth metal with the symbol Ba, and atomic number 56. It never occurs in nature in its pure form due to its reactivity with air, but combines with other chemicals such as sulfur or carbon and oxygen to form barium compounds that may be found as minerals. (L214, 408, L205)

科学粮草官-词典编辑部，修订于：2026-07-06

Toxicity

Symptoms

Ingesting excess barium may cause vomiting, abdominal cramps, diarrhea, difficulties in breathing, increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels may result in changes in heart rhythm or paralysis and possibly death. (L214)

Treatment

Intravenous infusion of potassium often relieves many of the symptoms of barium toxicity. (L214)

Toxicity Data

LD50: 250 mg/kg (Oral, Rat) (L273)

Health Effects

The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214)

Adverse Effects

ACGIH Carcinogen - Not Classifiable.

Exposure Routes

Oral (L214); inhalation (L214)

Toxicity Summary

Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214)

Minimum Risk Level

Intermediate Oral: 0.2 mg/kg/day (L134) Chronic Oral: 0.2 mg/kg/day (L134)

Carcinogen Classification

No indication of carcinogenicity to humans (not listed by IARC).