化合物详情

Calcium hypophosphite is completely disassociated in aqueous solution(1), therefore, volatilization from water surfaces is not expected to be an important fate process(SRC).

The calcium and potassium hypophosphites do not appear to be currently used as ingredients in foods as indicated by a survey of the food industry conducted by a National Research Council subcommittee in 1970 and more recent information obtained from industry by the Select Committee. They had limited medical use many years ago in tonics and as therapeutic agents but appear to be no longer used for these purposes(1).

IDENTIFICATION AND USE: Calcium hypophosphite (Ca(H2PO2)2) is a solid. This is a DEA List 1 chemical substance. It is used as a corrosion inhibitor, and in nickel plating. Calcium hypophosphite is also used as a pharmaceutic aid (retards oxidation of ferrous salts). It has been used as a veterinary dietary supplement. HUMAN STUDIES: There are no data available. ANIMAL STUDIES: The acute toxicity of calcium hypophosphite was investigated following a single oral administration to the Sprague Dawley rat followed by a 14-day observation period. Calcium hypophosphite was lethal in the rat following oral administration of a single dose at 2000 mg/kg. No mortality or severe signs of toxicity were observed following dosing at 300 mg/kg. Calcium hypophosphite was not mutagenic in Salmonella typh...

/ALTERNATIVE and IN VITRO TESTS/ Calcium hypophosphite was analyzed in vitro with the Hen's Egg Test - Chorioallantoic Membrane (HET-CAM) in vitro corrosion test. ... The final score is the sum of the effects on hemorragia, Lysis and coagulation. Final score after 3 min is 3.3 which corresponds to severe eye irritant.