化合物详情

This substance may be hazardous to the environment. Special attention should be given to water quality.

NIOSH (NOES Survey 1981-1983) has statistically estimated that 2,256 workers (657 of these are female) are potentially exposed to sulfuryl chloride in the US(1).

Ingestion Exposure: Abdominal pain. Burning sensation. Shock or collapse. See Inhalation.

LC50 (rat) = 159 ppm/4hr

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

The substance can be absorbed into the body by inhalation of its vapour.

The acute toxicity of sulfuryl chloride following inhalation is high. In male Sprague-Dawley rats with head-only exposure to vapor a 4 h-LC50 of 878 mg/m3 was calculated. Clinical signs included nasal discharge and eye irritation. In humans, pulmonary edema of delayed onset has been reported after inhalation of sulfuryl chloride vapor. Sulfuryl chloride hydrolyzes slowly in moist air and reacts violently with water, forming chlorosulfonic acid, hydrochloric acid and sulfuric acid. Due to this hydrolytic reaction, sulfuryl chloride is corrosive to the skin, eyes and respiratory tract. Studies with sulfuryl chloride concerning sensitizing properties are not available. The hydrolysis products sulfuric acid and hydrochloric acid gave no indication for a sensitizing potential in humans and e...

LD50 Rat, male, Sprague-Dawley, inhalation (4 hr) = 878 mg/cu m /(159 ppm)/ (sulfuryl chloride vapor, purity 100%)

Persons with pulmonary diseases

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... Consider administering a beta agonist such as albuterol for severe bronchospasm ... Monitor cardiac rhythm and treat arrhythmias as necessary ... Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's(LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopres...