化合物详情

Pesticide Ecotoxicity Data from EPA: 72

USDA APHIS Chemical Effects: collection=usda_chemeffect&query_type=synonym&query='^13071-79-9$'

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), terbufos, which has a vapor pressure of 0.00032 mm Hg at 20-25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase terbufos is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.6 hours(SRC), calculated from its rate constant of 2.4X10-10 cu cm/molecule-sec at 25 °C(SRC), that was derived using a structure estimation method(3). While terbufos was found to degrade in solution upon exposure to sunlight(4), no data were found regarding direct photolysis in air by sunlight.

Koc values ranging from 500 to 5000 have been reported for terbufos(1-4). According to a classification scheme(5), these Koc values suggest that terbufos is expected to have low to slight mobility in soil.

In soil, terbufos exhibited a half-life of 4 to 5 days. The sulfoxide formed by oxidation reached a maximum at about 14 days. The sulfone appeared one week after the start of incubation of soil with terbufos. Some other compounds observed in less than 1% amounts were the thiolophosphate, thiolophosphate sulfoxide and the thiolophosphate sulfone.

An estimated BCF of 560 was calculated for terbufos(SRC), using a log Kow of 4.48(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC).

The Henry's Law constant for terbufos is 0.000024 atm-cu m/mole(SRC), derived from its vapor pressure, 0.00032 mm Hg(1), and water solubility, 5.07 mg/l(2). This Henry's Law constant indicates that terbufos is expected to volatilize from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 2.8 days (SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 26 days(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column(SRC). The estimated volatilization half-life from a model pond is 43 days if adsorption...

The rate constant for the vapor-phase reaction of terbufos with photochemically-produced hydroxyl radicals has been estimated as 2.4X10-10 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1.6 hours at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(1). Terbufos does not contain functional groups that are expected to absorb light at wavelengths >290 nm, and would not be expected to be susceptible to direct photolysis by sunlight in air (SRC). Terbufos was incubated in natural, sterilized and distilled water, with an initial pH of 8.8 at 20 °C; it disappeared rapidly (half-life=3 days) in all systems(2). The half-lives of terbufos in distilled, deionized unbuffered water, and in buffered solution at p...

RAIN/SNOW/FOG: Terbufos was detected in arctic marine fog samples in Aug-Sept 1993 from the Bering and Chukchi Seas at a maximum concn of 12 ng/l(1). Terbufos was not detected in urban and agricultural rain sampled in Mississippi from Apr-Sept 1995(2).

Terbufos was qualitatively found as residue in samples tested during the Food and Drug Administration pesticide residue monitoring of various food samples for the test period of 1978-1982(1) and 1983-1986(2). Terbufos was detected in the ethyl acetate and dichloromethane extracts of brown rice, potato, cabbage, lettuce, carrot, cucumber, shiitake mushroom, apple, strawberry, and banana obtained from a local retail store in Japan(3). Of the 16,198 imported commodities sampled from Jan 1992-Mar 1994 in the US, terbufos was found in one sample of imported fresh pears (n=775), at a concn in the range of 0.05-0.1 ppm(4). Terbufos was not detected as residues during the 1992(5) and 1994(6) US regulatory monitoring studies.

Many of the organophosphorus insecticides are excreted in the milk ... /Organophosphorus insecticides/

Sediment from nine sampling sites located in the Suerte River basin in Costa Rica were analyzed for pesticides(1). Terbufos was detected in one of the nine samples from an open canal flowing from a banana packing facility at a concn of 154 ug/kg dry weight, and was not detected at the other sampling sites(1). Terbufos was detected in 2 of 32 samples in effluent from two banana packing plants in the Suerte River basin, Costa Rica(1).

The substance is very toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. Bioaccumulation of this chemical may occur in aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

RURAL/REMOTE: Terbufos was not detected in agricultural air sampled in Mississipppi from Apr-Sept 1995(1).

Terbufos' production may result in its release to the environment through various waste streams; its use as an insecticide(1) will result in its direct release to the environment(SRC).

SEDIMENT: Sediment from nine sampling sites located in the Suerte River basin in Costa Rica were analyzed for pesticides(1). Terbufos was detected in one of the nine samples from an open canal flowing from a banana packing facility at a concn of 154 ug/kg dry weight, and was not detected at the other sampling sites(1).

Secondary exposure of children through contact with their parents' contaminated clothing can also occur. /Organophosphorus pesticides/

Terbufos' production may result in its release to the environment through various waste streams; its use as an insecticide will result in its direct release to the environment. If released to air, a vapor pressure of 0.00032 mm Hg at 20-25 °C indicates terbufos will exist solely as a vapor in the ambient atmosphere. Vapor-phase terbufos will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.6 hours. Terbufos does not contain functional groups that are expected to absorb light at wavelengths >290 nm, and would not be expected to be susceptible to direct photolysis by sunlight in air. If released to soil, terbufos is expected to have low to slight mobility based upon Koc ranging from 500-5...

Ingestion Exposure: Blurred vision. Headache. Dizziness. Muscle spasms. Weakness. Vomiting. Diarrhoea. Abdominal pain.

Because different classes of enzymes may be inhibited, the effects of organophosphorus pesticide poisoning may be complex and potentially at least could involve interactions with drugs as well as with other pesticides or chemicals. Potentiation may also involve solvents or other components of formulated pesticides. Certain drugs such a phenothiazines, antihistamines, CNS depressants, barbiturates, xanthines (theophylline), aminoglycosides and parasympathomimetic agents are to be avoided because of increased toxicity. /Organophosphorus pesticides/

ACGIH Carcinogen - Not Classifiable.

The substance can be absorbed into the body in hazardous amounts by ingestion, by inhalation and through the skin.

Oral Subchronic Chronic Reference Dose Reference: HEAST Current

/SIGNS AND SYMPTOMS/ Principal effects /of anticholinesterases as toxic components of insecticides/ on eye, whether from local contact or systemic poisoning, are miosis and spasm of accommodation for near vision. /Anticholinesterases/

FAO/WHO ADI: 0.0002 mg/kg

Soil Saturation Concentration (mg/kg): 3.09e+01

Soil Saturation Concentration (mg/kg): 3.09e+01

Reference: Smith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP