化合物详情

CAS15500-66-0

分子式C35H60Br2N2O4

分子量732.67 g/mol g/mol

危化品

Pancuronium bromide is a bromide salt consisting of two bromide ions and one pancuronium dication. It has a role as a cholinergic antagonist, a nicotinic antagonist and a muscle relaxant. It contains a pancuronium.

科学粮草官-词典编辑部，修订于：2026-07-06

Toxicity

Drug Induced Liver Injury

References: DOI:10.1016/j.drudis.2016.02.015

Non-Human Toxicity Excerpts

... Little is known about the cardiovascular responses of the anemic fetus ti neuromuscular blockade. ... Despite marked anemia with potentially decr cardiac reserve, the fetal responses to pancuronium neuromuscular blockade would differ significantly when compared with atracurium (a cardiovascular sparing agent). Ten fetal sheep (137 +/- 1 (SE) days gestation) were divided into three groups (21 experiments): Pancuronium (n = 7), atracurium (n = 6) and control (n = 8). Fetal anemia (Hct = 21.8 +/- 0.7%) was produced by serial hemorrhage over 3 days. Fetal arterial (FAP) and venous (FVP) pressures, heart rate (FHR) and arterial pH, pO2 and PCO2 were measured at -20, 0, 10, 20, 30,60 and 90 min relative to neuromuscular blockade. Data were analyzed by three way ANOVA for repeated measures...

Effects During Pregnancy and Lactation

◉ Effects on Lactation and Breastmilk