化合物详情
CAS16893-85-9
分子式Na2SiF6
分子量188.05 g/mol
危化品
See also: A01 CELLULAR RECHARGE (FDA NDC: 63479-0101) (component of); alkali fluorosilicates(Na) (annotation moved to); Sodium fluorosilicate (annotation moved to).
科学粮草官-词典编辑部,修订于:2026-07-06

Toxicity
ToxicityProbable Routes of Human Exposure
AVOID INHALATION OF DUSTS
Symptoms
Ingestion Exposure: Abdominal cramps. Burning sensation. Nausea. Vomiting. Sore throat. Weakness. Convulsions. Shock or collapse.
Toxicity Data
LCLo (humans) = 33 mg/m3/6h
Exposure Routes
The substance can be absorbed into the body by ingestion.
Human Toxicity Excerpts
A 2 1/2-year old girl ingested sodium silicofluoride, developed acute respiratory failure, a prolonged AT interval, ventricular tachycardia and fibrillation, hypokalemia, hypocalcemia (3 to 4 mg/100 ml), and aspiration pneumonia.
Non-Human Toxicity Values
LD50 Rat oral 125 mg/kg
Non-Human Toxicity Excerpts
DAIRY HERD OF 600 ANIMALS BECAME POISONED AS A RESULT OF RAILCAR CONTAMINATION OF FEED; 95% OF HERD AFFECTED WITH SIGNS OF DECR NEUROMUSCULAR TRANSMISSION. TREATMENT WITH CALCIUM GLUCONATE IV WAS EFFECTIVE. ACUTE POISONING RESEMBLED CALCIUM DEPLETION.
Antidote and Emergency Treatment
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist ey...





