化合物详情

LC50 Nitocra spinipes (Harpacticoid copepod) 1.3 mg/L/96 hr (95% confidence limit: 1.0-1.7 mg/L); static /formulated product/

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), isodecyl alcohol, which has an estimated vapor pressure of 2.1X10-2 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase isodecyl alcohol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 25 hours(SRC), calculated from its rate constant of 1.5X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of isodecyl alcohol can be estimated to be 81(SRC). According to a classification scheme(2), this estimated Koc value suggests that isodecyl alcohol is expected to have high mobility in soil.

AEROBIC: In sewage, isodecyl alcohol gave a theoretical oxygen demand of 24, 44, 42 and 39 percent in 5, 10, 15 and 20 days, respectively(1). In acclimated sewage isodecyl alcohol gave theoretical oxygen demand of 14, 26, 45 and 32 percent in 5, 10, 15 and 20 days, respectively(1). Isodecyl alcohol gave theoretical oxygen demand of 6, 17, 34 and 40 percent in 5, 10, 15 and 20 days, respectively, in seawater(1). In a manometric study of poorly soluble compounds, isodecyl alcohol degraded 17.4 and 22.4 percent of ultimate BOD/theoretical oxygen demand with 10 minutes of sonification(2).

An estimated BCF of 145 was calculated for isodecyl alcohol(SRC), using an estimated log Kow of 3.71(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC), provided the compound is not metabolized by the organism(SRC).

The Henry's Law constant for isodecyl alcohol is estimated as 5.5X10-5 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that isodecyl alcohol is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 24 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 11 days(SRC). Isodecyl alcohol's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Isodecyl alcohol is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.07X10-2 mm...

The rate constant for the vapor-phase reaction of isodecyl alcohol with photochemically-produced hydroxyl radicals has been estimated as 1.5X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 25 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Isodecyl alcohol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2).

This substance may be hazardous to the environment. Special attention should be given to fish.

Isodecyl alcohol's use as an intermediate for the production of plasticizers(1) and as an antifoaming agent in textile processing(2) may result in its release to the environment through various waste streams(SRC).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 32,203 workers (4507 of these are female) are potentially exposed to isodecyl alcohol in the US(1). Occupational exposure to isodecyl alcohol may occur through dermal contact with this compound at workplaces where isodecyl alcohol is produced or used(SRC). The general population may be exposed to isodecyl alcohol dermal contact with products containing isodecyl alcohol(SRC).

Isodecyl alcohol's as an intermediate for the production of plasticizers and as an antifoaming agent in textile processing may result in its release to the environment through various waste streams. If released to air, an estimated vapor pressure of 2.1X10-2 mm Hg at 25 °C indicates isodecyl alcohol will exist solely as a vapor in the atmosphere. Vapor-phase isodecyl alcohol will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 25 hours. If released to soil, isodecyl alcohol is expected to have high mobility based upon an estimated Koc of 80. Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law constant of 5.5X10-5 atm-cu m/mole. The...

Ingestion Exposure: Diarrhoea. Vomiting. Further see Inhalation.

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

/SIGNS AND SYMPTOMS/ Direct contact with skin can produce irritation. ... Vapors are non-irritating to the eyes and throat. Causes smarting of skin and first-degree burns on short exposure; may cause secondary burns on long exposure.

Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques, with a bag-valve-mask device, may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Monitor for signs of hypoglycemia (decreased LOC, tachycardia...