化合物详情

Pesticide Ecotoxicity Data from EPA: 102

EXPERIMENTAL: In lactating goats concentrations of carbon-14 label in milk were measured after giving capsules containing a 9:1 mixture of 14C-glyphosate and 14C-aminomethylphosphonic acid (AMPA) to a dose level equivalent to 120 mg/kg diet (expressed as free acid) for 5 days. Concentrations in milk (as mg equivalents glyphosate/kg whole milk) ranged from 0.019 to 0.086 mg/kg during the test period; at day 5 after the last dose the concentration was 0.006 mg/kg.

LC50 (rat) > 0.0013 mg/m3/4h

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

IDENTIFICATION AND USE: Glyphosate isopropylamine salt is a white odorless powder that is commonly used as a herbicide to control broadleaf weeds and grasses, in many food and non-food crops. It is an active ingredient in the herbicide Roundup. HUMAN EXPOSURE AND TOXICITY: Clinical experiences with patients exposed to Roundup either accidentally or through deliberate ingestion have been reported by investigators. Symptoms resulting from dermal exposure incidental to the use of the product included periorbital edema and chemosis of the eye, cardiovascular effects (tachycardia and elevated blood pressure), swelling and paraesthesia at the site of dermal contact and prolonged skin irritation. Deliberate ingestion resulted in more severe effects, including lethality from apparent respirator...