化合物详情

CAS74115-24-5

分子式C14H8Cl2N4

分子量303.15 g/mol g/mol

危化品

Clofentezine is a tetrazine that is 1,2,4,5-tetrazine in which both of the hydrogens have been replaced by o-chlorophenyl groups. It has a role as a mite growth regulator and a tetrazine acaricide. It is an organochlorine acaricide, a tetrazine and a member of monochlorobenzenes. It derives from a hydride of a 1,2,4,5-tetrazine.

科学粮草官-词典编辑部，修订于：2026-07-06

Toxicity

EPA Ecotoxicity

Pesticide Ecotoxicity Data from EPA: 34

Effect Level

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Target Organs

Hepatic

Lethal Dose

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Toxicity Data

Oral (rat) > 5200 mg/kg Dermal (rat) > 2100 mg/kg Inhalation (rat) > 0.89 (mg/l)

Health Effects

No adverse health effects attributable to clofentezine were detecte during medical surveillance between 1985 and 2004 in workers at a plant manufacturing clofentezine. The medical examination included an extensive physical examination (including height, body weight, skin, ear, nose and throat, and respiratory, nervous, alimentary, reticulo-endothelial and cardiovascular systems, and locomotion) and specific tests for blood pressure and vision. The examination also included tests for hearing, lung function, urine analysis and blood tests when these were considered appropriate. (Makhteshim Agan Industries Ltd, 2004). However, there is an increase of incidences of thyroid adenomas, adenocarcinomas, thyroid hyperplasia, agglomeration of colloid and thyroid hormones in rats receiving prolong...

Screening Level

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Effect Concentration

collection=toxvaldb&kind=^EC$

Lethal Concentration

collection=toxvaldb&kind=^LC$

RAIS Toxicity Values

Oral Slope Factor Reference: OPP

Carcinogen Classification

Not listed by IARC.

Reference and Risk Values

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1 or Cancer Risk Level 1E-06

Fraction of Contaminant Absorbed Dermally from Soil: 0.1

Hazard Quotient Level 3 or Cancer Risk Level 1E-04

Fraction of Contaminant Absorbed Dermally from Soil: 0.1