化合物详情
CAS87760-53-0
分子式C21H29N5O2
分子量383.49 g/mol g/mol
危化品
Tandospirone is a dicarboximide that is (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione which is substituted by a 4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl group at position 2. It is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM). It has a role as an antidepressant and an anxiolytic drug. It is a dicarboximide, a bridged compound, a member of pyrimidines, a N-alkylpiperazine and a N-arylpiperazine. It is a conjugate base of a tandospirone(1+).
科学粮草官-词典编辑部,修订于:2026-07-06

Toxicity
ToxicityDrug Induced Liver Injury
References: DOI:10.1016/j.drudis.2019.09.022





