化合物详情

Likelhood score: D (possible rare cause of clinically apparent liver injury).

Reports of hypoglycemia are more frequent when repaglinide is used in combination with metformin, while studies suggest an increased risk of peripheral edema if used in combination with a thiazolidinedione.

In unintentional excessive ingestion, prompt feeding may be sufficient to alleviate symptoms. In more severe cases, glucagon subcutaneous or intramuscular injection is recommended (1 mg for weights greater than 25 kg). Failure to respond to glucagon should be addressed with a 20% glucose intravenous infusion.

References: DOI:10.1016/j.drudis.2019.09.022

◉ Effects on Lactation and Breastmilk