化合物详情

CAS137234-62-9

分子式C16H14F3N5O

分子量349.31 g/mol g/mol

危化品

Voriconazole is a triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4. It has a role as a P450 inhibitor. It is a tertiary alcohol, a difluorobenzene, a member of pyrimidines, a conazole antifungal drug and a triazole antifungal drug.

科学粮草官-词典编辑部，修订于：2026-07-06

Toxicity

Effect Level

collection=toxvaldb&kind=^EL$

Hepatotoxicity

Likelihood score: B (likely cause of clinically apparent liver injury).

Carcinogen Classification

Evaluation Year: 2024

Drug Induced Liver Injury

References: DOI:10.1016/j.drudis.2019.09.022

Effects During Pregnancy and Lactation

◉ Effects on Lactation and Breastmilk