化合物详情

CAS2192-20-3
分子式C21H27ClN2O2 · 2HCl
分子量447.83 g/mol g/mol
危化品

Hydroxyzine Hydrochloride is the hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05)

科学粮草官-词典编辑部,修订于:2026-07-06

化合物详情

Toxicity

Toxicity
2
Lethal Dose
collection=toxvaldb&kind=^LD$
Drug Induced Liver Injury
References: DOI:10.1016/j.drudis.2016.02.015
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