化合物详情

In the atmosphere, particulate bound mercury constitutes only approximately 2% of total mercury in the air and has normally been found to be less than 0.1 ng/cu m in regions unaffected by local sources(1). Some other mercury compounds which may exist in the atmosphere are mercuric chloride, mercuric bromide, mercuric hydroxide, mercuric sulfide, and mercuric cyanide(1). The rest is elemental mercury in the gaseous phase. In remote areas over the Atlantic and Pacific oceans, mercury bound to particulate matter concns are generally at or below the picogram per cubic meter level(1).

Common symptoms include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), edema (swelling), and desquamation (dead skin peels off in layers). (A5)

EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.

LD50: 35 mg/kg (Oral, Mouse) (L943) LD50: 40 mg/kg (Oral, Rat) (L943) LD50: 100 mg/kg (Dermal, Rat) (L943)

Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from som...

ACGIH Carcinogen - Not Classifiable.

Oral (L7); inhalation (L7); dermal (L7)

High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein...

Chronic Inhalation: 0.0002 mg/m3 (Mercury) (L134)

Contact with eyes causes ulceration of conjunctiva & cornea.

3, not classifiable as to its carcinogenicity to humans. (L135)