(−)-表儿茶素(EC)属于黄烷醇类化合物，在可可和可可产品中大量存在。表儿茶素的化学结构由1个4-羟基含氧杂环连接2个苯环组成。 应用 (−)-表儿茶素(EC)已用于： 在体内（高脂喂养小鼠）和体外（HepG2细胞）研究中，作为抗氧化剂下调烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶水平和提高胰岛素敏感性。 研究其对边缘高血压大鼠(BHR)模型血压、一氧化氮合酶(NOS)活性和类焦虑行为的影响 使用氧化应激参数检测其对游泳训练中的中年小鼠海马体神经元存活情况的影响。 研究其在黑巧克力中的抗氧化性 作为多酚分析的特征化合物 Gene Information human ... BACE1(23621), CYP1A2(1544) (−)-Epicatechin (EC) belongs to the group of flavanols and is abundantly present in cacao and cacao products. The chemical structure of EC includes an oxygenated heterocycle with a 4-hydroxyl group linked with two aromatic rings. Application (−)-Epicatechin (EC) has been used: as an antioxidant to downregulate nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase and improve insulin sensitivity in in vivo (high fat-fed mice) and in vitro (HepG2 cells) studies to study its effect on blood pressure, nitric oxide synthase (NOS) activity and anxiety-like behavior on borderline hypertensive rat (BHR) models to test its effect on neuronal survival in the hippocampus of middle-aged rats on swimming training, under oxidative stress to study its antioxidant activity in dark chocolate as a characteristic compound in polyphenols analysis