4-Bromophenyl methyl sulfone may be used to synthesize: • biaryl methyl sulfones • 5-[[-4-(methylsulfonyl)phenyl]thio]thiophene-2-sulfonamide • 1-[4-(methylsulfonyl)phenyl]-1H-pyrazole (Hmsppz) • DuP 697 via reaction with (5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)trimethylsilane 4-Bromophenyl methyl sulfone (1-bromo-4-(methylsulfonyl)benzene) can undergo coupling reaction with benzene sulfonamide in the presence of copper(I)iodide to form the corresponding N-aryl sulfonamide. 4-Bromophenyl methyl sulfone may be used to synthesize: • biaryl methyl sulfones • 5-[[-4-(methylsulfonyl)phenyl]thio]thiophene-2-sulfonamide • 1-[4-(methylsulfonyl)phenyl]-1H-pyrazole (Hmsppz) • DuP 697 via reaction with (5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)trimethylsilane 4-Bromophenyl methyl sulfone (1-bromo-4-(methylsulfonyl)benzene) can undergo coupling reaction with benzene sulfonamide in the presence of copper(I)iodide to form the corresponding N-aryl sulfonamide.