用作以下过程的反应物： • 制备靶向信号转导子src同源区2 （SH2）结构域和转录激活子3 （Stat3）的磷酸肽模拟前药 • 采用铃木偶联和拆分为关键步骤的多步合成法，合成结核分枝杆菌蛋白酪氨酸磷酸酶抑制型二氟甲基膦酸衍生物 • 碱性水解时P-C键裂 • 制备蛋白酪氨酸磷酸酶1B （PTP1B）抑制剂（非水解二氟甲基膦酸酯部分）胞内递送前药 Reactant for: · Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3) · Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps · P-C bond cleavage on basic hydrolysis · Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)