Methyl picolinate (MP) exists in two conformers i.e s-trans and s-cis. Molecular structure of these forms has been investigated by gas electron diffraction. Methyl picolinate (MP) exists in two conformers i.e s-trans and s-cis. Molecular structure of these forms has been investigated by gas electron diffraction. Methyl picolinate may be used in the synthesis of: 3-substituted-imidazo[1,5-α]pyridines N-benzylpicolinamide 3-phenylsubstituted imidazo[1,5-α]pyridines pyrimine 4,6-dipyridylpyrimidine