以 4-甲氧基吡啶- N -氧化物为原料，经催化加氢制备 4-甲氧基吡啶。研究了以均三甲苯锂为金属碱的 4-甲氧基吡啶的邻位锂化反应。 4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied. Used in an efficient construction of dihyropyridin-4-ones potential ligands for neuronal nicotinic acetycholine receptors.