天然但非蛋白原氨基酸；用于肌肉蛋白破裂的引发剂。 Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. Applications： The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.