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Nivalenol is a type - B trichothecene mycotoxin, produced by molds such as Fusarium cerealis, Fusarium graminearum. Nivalenol may be formed by higher plants and by mamals, as a productt of biodegradation of other thrichothecenes.Nivalenol (0.01 mg/ml) induces apoptosis in HL60 cells (Ueno et al., 1995). Nivalenol was shown to inhibit protein synthesis in rabbit reticulocytes in vitro. Nivalenol inhibited the synthesis of nucleic acids in vitro (Ueno and Fukushima, 1968) Nivalenol is a type - B trichothecene mycotoxin, produced by molds such as Fusarium cerealis, Fusarium graminearum. Nivalenol may be formed by higher plants and by mamals, as a productt of biodegradation of other thrichothecenes. Nivalenol (0.01 mg/ml) induces apoptosis in HL60 cells (Ueno et al., 1995). Nivalenol was shown to inhibit protein synthesis in rabbit reticulocytes in vitro. Nivalenol inhibited the synthesis of nucleic acids in vitro (Ueno and Fukushima, 1968)
中文名称
雪腐镰刀菌烯醇
英文名称
Nivalenol from Fusarium nivale
中文别名
3α,4β,7α,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one
英文别名
Trichothec-9-en-8-one,12,13-epoxy-3a,4b,7a,15-tetrahydroxy-(8CI) | 12,13-Epoxy-3a,4b,7a,15-tetrahydroxytrichothec-9-en-8-one | 3a,4b,7a,15-Tetrahydroxyscrip-9-en-8-one | NSC 269143 | Nivalenol | NSC 269143 | 12,13-EPOXY-3.ALPHA.,4.BETA.,7.ALPHA.,15-TETRAH
CAS号
23282-20-4
分子式
C15H20O7
分子量
312.3 g/mol
精确质量
≥99%(HPLC)
PSA
120.000 Ų
Logp
-1.700
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生物毒素/乙腈中雪腐镰刀菌烯醇 100μg/mL 1mL

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