Acivicin hydrochloride

盐酸阿西维星

Acivicin hydrochloride

A656031-1ml

1ml

10mM in DMSO

充氩,-80℃储存

超低温冰袋运输

Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties In Vitro Acivicin hydrochloride (AT-125 hydrochloride; 0.1-50 μM; 5 days) has an IC 50 of 0.7 μM in human HepG2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Acivicin hydrochloride (AT-125 hydrochloride; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to TolueneDosage: 5 mg/kg Administration: IP; twice weekly (monday and wednesday) Result: Reduced urinary γ-GT by 70-78%. IC50& Target:γ-glutamyl transpeptidase

盐酸阿维菌素（AT-125 hydrochloride）是一种由链霉菌（Streptomyces sviceus）产生的天然产物，是一种γ-谷氨酰转肽酶（GGT）抑制剂。盐酸阿维菌素可透过血脑屏障，具有抗癌、抗寄生虫等特性[......]。

161922-40-3(DMSO)

C5H8Cl2N2O3

215.03 g/mol

C1C(ON=C1Cl)C(C(=O)O)N.Cl