AChE/BChE-IN-10

AChE/BChE-IN-10

A658702-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

AChE/BChE-IN-10 (Compound 7b) is a potent dual AChE and BChE inhibitor with IC 50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 shows good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation and be used in Alzheimer’ Appearance:Solid IC50& Target:AChE 0.176 μM (IC 50 ) BChE 0.47 μM (IC 50 ) In Vitro:AChE/BChE-IN-10 inhibits AChE in a non-competitive manner with K i of 0.21 μM, and BChE in a mixed-fashion with K i of 0.15 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:AChE/BChE-IN-10 (Compound 7b) is a potent dual AChE and BChE inhibitor with IC 50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 shows good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation and be used in Alzheimer’

C26H30N2O2

402.53 g/mol

O=C(NCCC1CCN(CC2=CC=CC=C2)CC1)C3=CC=C4C=C(OC)C=CC4=C3

DMSO : 25 mg/mL (62.11 mM; ultrasonic and warming and heat to 60°C)