AZ13824374

AZ13824374

A658945-5mg

5mg

≥98%

2-8°C储存,避光,干燥

冰袋运输

AZ13824374 is a highly potent and selective ATAD2 bromodomain inhibitor which shows cellular target engagement and antiproliferative activity in a range of breast cancer models. AZ13824374 inhibits ATAD2 with pIC 50 s of 8.2 and 6.2 in ATAD2 FRET assay an Appearance:Solid Biological Activity:AZ13824374 is a highly potent and selective ATAD2 bromodomain inhibitor which shows cellular target engagement and antiproliferative activity in a range of breast cancer models. AZ13824374 inhibits ATAD2 with pIC 50 s of 8.2 and 6.2 in ATAD2 FRET assay an

C30H39FN8O2

562.68 g/mol

O=C1N[C@H](C(C)C)[C@H]2C3=CC=CC=C3C[C@@H]1N2C(C4=NN5C(C(NC6CCN(CC(C)(F)C)CC6)=C4)=NN=C5C)=O

DMSO : ≥ 200 mg/mL (355.44 mM)