Angiopep-2 hydrochloride

血管肽-2盐酸盐

Angiopep-2 hydrochloride

A659118-5mg

5mg

≥99%

干燥,-80℃储存

超低温冰袋运输

Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer. Appearance:Solid In Vitro:Paclitaxel is conjugated to a brain peptide vector, Angiopep-2, to provide a paclitaxel– Angiopep-2 conjugate named ANG1005. ANG1005 enters the brain to a greater extent than paclitaxel and bypasses the P-gp. ANG1005 has an antineoplastic potency similar In Vivo:ANG1005 administration leads to a significant increase in the survival of mice with intracerebral implantation of U87 MG glioblastoma cells or NCI-H460 lung carcinoma cells. MCE has not independently confirmed the accuracy of these methods. They are Biological Activity:Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.

C104H150ClN29O31

2337.93 g/mol

H2O : 100 mg/mL (42.77 mM; Need ultrasonic)