Aprocitentan-d4

阿普罗西坦-d4

Aprocitentan-d4

A659393-5mg

5mg

≥97%

-20°C储存

超低温冰袋运输

Aprocitentan-d 4 is a deuterium labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively. Appearance:Solid IC50& Target:ET A 3.4 nM (IC 50 ) ET A 6.7 (pA2) ET B 987 nM (IC 50 ) ET B 5.5 (pA2) Biological Activity:Aprocitentan-d 4 is a deuterium labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.

C16H10D4Br2N6O4S

550.22 g/mol

O=S(N)(NC1=NC=NC(OC([2H])([2H])C([2H])([2H])OC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O