ALX 40-4C Trifluoroacetate

ALX 40-4C 三氟乙酸盐

ALX 40-4C Trifluoroacetate

A659408-5mg

5mg

≥96%

-20°C储存,干燥

超低温冰袋运输

对湿度敏感

ALX 40-4C Trifluoroacetate 是一种趋化因子受体 (CXCR4) 抑制剂，能够抑制 SDF-1 与 CXCR4 结合，Ki 值为 1 μM，具有抗 HIV-1 作用；ALX 40-4C Trifluoroacetate 同时为 APJ 受体拮抗剂，IC50 值为 2.9 μM。 序列 Ac-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-NH2 ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.

143413-49-4(free)

C56H113N37O10(free)

1464.74(free) g/mol

H2O : 50 mg/mL (31.67 mM; Need ultrasonic)