Recombinant alpha Tubulin Antibody

抗体

微管蛋白α/Tubulin α（内参）抗体 | 微管蛋白α抗体 | 微管蛋白α单克隆抗体 | 微管蛋白α重组单克隆抗体 | alpha Tubulin抗体 | alpha Tubulin单克隆抗体 | alpha Tubulin重组单克隆抗体 | TUBA4A抗体 | TUBA4A单克隆抗体 | TUBA4A重组单克隆抗体

Alpha-tubulin 1 antibody | ALS22 antibody | B ALPHA 1 antibody | bA408E5.3 antibody | H2 ALPHA antibody | Hum a tub1 antibody | Hum a tub2 antibody | LIS3 antibody | MGC171407 antibody | MGC55332 antibody | TBA4A_HUMAN antibody | Testis-specific alpha-tub

Liquid

Ab088465-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4.

0.02% Sodium azide

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Post-translational: Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules. Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.

A synthetic peptide derived from human alpha 4A Tubulin (AA 10-51).

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

alpha Tubulin

WB: Mouse brain, HeLa, Hep G2, Jurkat, HEK293, NIH/3T3 and C6 lysates. IHC: Human breast cancer tissue. IF/ICC: HeLa, Hep G2 cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG