Recombinant APC Antibody

抗体

APC抗体 | APC重组兔单抗 | 重组APC抗体 | 腺瘤样息肉抗体 | 腺瘤样息肉单克隆抗体 | 腺瘤样息肉重组单克隆抗体 | APC抗体 | APC单克隆抗体 | APC重组单克隆抗体

adenomatosis polyposis coli tumor suppressor | adenomatosis polyposis coli | adenomatous polyposis coli protein | adenomatous polyposis coli | APC | BTPS2 | Deleted in polyposis 2.5 | DP2 | DP2.5DP2 | DP3 | FPC | GS | Min | Protein APC | Adenomatous Polyp

Liquid

Ab089133-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4

0.01% Sodium azide

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

A synthetic peptide derived from human APC (AA 72-90)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

APC

WB: K562, HT-29, NIH/3T3 and C6 cell lysates. ICC/IF: LNCaP cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG