Recombinant beta Catenin Antibody

抗体

beta-连环素抗体 | beta-连环素单克隆抗体 | beta-连环素重组单克隆抗体 | beta Catenin抗体 | beta Catenin单克隆抗体 | beta Catenin重组单克隆抗体 | CTNNB1抗体 | CTNNB1单克隆抗体 | CTNNB1重组单克隆抗体

b-catenin antibody | Beta catenin antibody | Beta-catenin antibody | Cadherin associated protein antibody | Catenin (cadherin associated protein), beta 1, 88kDa antibody | Catenin beta 1 antibody | Catenin beta-1 antibody | CATNB antibody | CHBCAT antibod

Liquid

Ab091079-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4

0.01% Sodium aizde

Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.

A synthetic peptide derived from human beta Catenin (AA 663-681).

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

beta Catenin

WB: HeLa, NIH/3T3 and C6 cell lysates. ICC/IF: 293T cells

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG