Recombinant beta III Tubulin Antibody

抗体

神经细胞特异性微管蛋白内参抗体 | 神经细胞特异性微管蛋白抗体 | 神经细胞特异性微管蛋白单克隆抗体 | 神经细胞特异性微管蛋白重组单克隆抗体 | beta III Tubulin抗体 | beta III Tubulin单克隆抗体 | beta III Tubulin重组单克隆抗体 | TUBB3抗体 | TUBB3单克隆抗体 | TUBB3重组单克隆抗体

beta 3 tubulin antibody | beta 4 antibody | beta-4 antibody | CDCBM antibody | CDCBM1 antibody | CFEOM3 antibody | CFEOM3A antibody | FEOM3 antibody | M(beta)3 antibody | M(beta)6 antibody | MC1R antibody | Neuron specific beta III Tubulin antibody | Neur

Liquid

Ab091169-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4.

0.02% Sodium azide

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Post-translational: Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules.

A synthetic peptide derived from human beta III Tubulin (AA 400-450).

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

beta III Tubulin

WB: HeLa, Hep G2,and A375 cell lysates. IHC: Human thyroid cancer tissue. IF/ICC: HeLa, A431 cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG