DNA Polymerase iota Mouse mAb

抗体

DNA Polymerase iota抗体 | DNA Polymerase iota单克隆抗体 | DNA聚合酶I抗体

DNA polymerase iota antibody | Eta 2 antibody | Eta2 antibody | POLI antibody | POLI_HUMAN antibody | Polymerase (DNA directed) iota antibody | RAD 30B antibody | RAD30 homolog B antibody | RAD30 | RAD30B antibody | RAD3OB antibody | S. cerevisiae | homol

Liquid

Ab100101-10μl

10μl

已验证

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

0.02% Sodium azide

Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.

Recombinant protein of human DNA Polymerase iota (AA 458-740) produced in E.coli.

小鼠(Mouse)

人(Human)

DNA Polymerase iota

WB: HEK293T transfected with pCMV6-ENTRY POLI cDNA for 48 hrs; HepG2, HeLa, SVT2, A549 lysates. IHC: Human ovary adenocarcinoma tissue.

150 kDa

Unconjugated

Mouse IgG1

单克隆抗体

Protein G purified

OTI3B5

Whole IgG