Recombinant hnRNP Q Antibody

抗体

Glycine- and tyrosine-rich RNA-binding protein | GRY-RBP | hnRNP Q | NS1-associated protein 1 | Synaptotagmin-binding, cytoplasmic RNA-interacting protein | cytoplasmic RNA-interacting protein | dJ3J17.2 | Glycine and tyrosine rich RNA binding protein | G

Liquid

Ab108467-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4

0.01% Sodium azide

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.

A synthetic peptide derived from human hnRNP Q (AA 603-616)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

SYNCRIP

WB: K562, Hep G2 and C6 cell lysates. IHC: Human tonsil tissue. ICC/IF: HeLa cells

150 kDa

Unconjugated

Rabbit IgG

重组抗体

Protein A purified

Whole IgG