MAFB Antibody

抗体

MAFB抗体 | MAFB多克隆抗体

Kreislerantibody | Kreisler (mouse) maf related leucine zipper homologantibody | Kreisler maf related leucine zipper homologantibody | KRML antibody | MAF bZIP transcription factor B antibody | Maf-B antibody | Mafb antibody | MAFB/Kreisler basic region/l

Liquid

Ab113986-10μl

10μl

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4

0.05% Sodium azide

Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Post-translational: Phosphorylated by GSK3 and MAPK13 on serine and threonine residues. Sumoylated. Sumoylation on Lys-32 and Lys-297 stimulates its transcriptional repression activity and promotes macrophage differentiation from myeloid progenitors.

A synthetic peptide derived from human MAFB.

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

MAFB

WB: SKOV3, Jurkat lysates. IHC: Human thyroid cancer, breast cancer tissues.

150 kDa

Unconjugated

Rabbit IgG

多克隆抗体

Antigen affinity purified

Whole IgG