Recombinant Mitofusin 2 Antibody

抗体

线粒体融合蛋白Mfn2重组抗体 | 重组线粒体融合蛋白 2 抗体

CMT2A antibody | CMT2A2 antibody | CPRP 1 antibody | CPRP1 antibody | EC 3.6.5.- antibody | Fzo antibody | HSG antibody | hyperplasia suppressor gene antibody | Hypertension related protein 1 antibody | KIAA0214 antibody | MARF antibody | MFN 2 antibody |

Liquid

Ab115473-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

0.02% Sodium azide

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

A synthetic peptide derived from human Mitofusin 2 (AA 50-100)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

MFN2

WB: Hep G2, K562, NIH/3T3 and C6 cell lysates. IHC: Human breast carcinoma tissue. ICC/IF: HeLa cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG