PSMA7/HSPC Mouse mAb

抗体

蛋白酶体PSMα7抗体 | 蛋白酶体PSMα7单克隆抗体

C6 | HSPC | RC6-1 | XAPC7 | HEL-S-276 | C6 antibody HSPC | Proteasome (prosome macropain) subunit alpha type 7 | XAPC7 antibody | Proteasome alpha 7 subunit | Proteasome subunit alpha 4 | Proteasome subunit alpha type 7 | Proteasome subunit alpha type-7 |

Liquid

Ab123656-10μl

10μl

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

0.02% Sodium azide

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

Recombinant full length protein of human PSMA7 produced in HEK293T.

小鼠(Mouse)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

PSMA7

WB: HEK293T transfected with pCMV6-ENTRY PSMA7 cDNA for 48 hrs, A549, MCF7, 293T, HeLa, A431, Raji, HepG2, K562, COLO205 lysates. IHC: Human breast, pancreas, thyroid tissues.

150 kDa

Unconjugated

Mouse IgG2b

单克隆抗体

Protein A purified

OTI5F6

Whole IgG