Recombinant RAB7 Antibody

抗体

RAS癌基因相关蛋白抗体 | RAS癌基因相关蛋白单克隆抗体 | RAS癌基因相关蛋白重组单克隆抗体 | RAB7抗体 | RAB7单克隆抗体 | RAB7重组单克隆抗体

CMT2Bantibody | PRO2706 antibody | PSN antibody | RAB7, member RAS oncogene family antibody | RAB7A antibody | RAB7A, member RAS oncogene family antibody | RAB7A_HUMAN antibody | Ras associated protein RAB7antibody | Ras related protein Rab7 antibody | Ra

Liquid

Ab124248-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。

50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4

0.01% Sodium azide

Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function (e.g. Mycobacterium). In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA. Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation.

A synthetic peptide derived from human RAB7 (AA 185-200)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

RAB7

WB: Hep G2, MCF7, A431, A375, K562, HeLa, NIH/3T3 and C6 cell lysates. IHC: Mouse colon tissue. ICC/IF: HeLa cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG