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商品详情
名称
Recombinant Septin 2 Antibody
分子类型
抗体
别名
败血症2抗体 | 败血症2重组抗体
英文别名
DIFF6 antibody | hNEDD5 antibody | KIAA0158 antibody | NEDD 5 antibody | NEDD-5 antibody | NEDD5 antibody | Neural precursor cell expressed developmentally down regulated 5 antibody | Neural precursor cell expressed developmentally down regulated protein
物理外观
Liquid
货号
Ab127087-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂
0.02% Sodium azide
生化机理
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
免疫原
A synthetic peptide derived from human Septin 2 (AA 250-300).
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
SEPTIN2
阳性对照
WB: Jurkat, HeLa, MCF7, Hep G2, HEK293, SH-SY5Y, NIH/3T3 and C6 cell lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
多克隆抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
危险属性
「暂无危险属性」
上下游信息
「暂无上下游信息」
技术文档
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Recombinant Septin 2 Antibody 重组 10μl

品牌:阿拉丁
货号:Ab127087-10μl
级别: 重组
货期:30天
已售 226 件
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10μl

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